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5' exonuclease assay for detection of serogroup Y Neisseria meningitidis.

ABSTRACT: The incidence of serogroup Y meningococcal disease has increased recently in the United States. Here, we describe the development of a 5' exonuclease assay for the detection of serogroup Y Neisseria meningitidis and demonstrate the usefulness of this assay for resolving serogroup identification of strains that are resistant to conventional serogrouping and for the nonculture identification of serogroup Y meningococcal disease.

SUBMITTER: Probert WS

PROVIDER: S-EPMC139717 | biostudies-literature | 2002 Nov

REPOSITORIES: biostudies-literature

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5' exonuclease assay for detection of serogroup Y Neisseria meningitidis.

Probert William S WS Bystrom Susan L SL Khashe Shideh S Schrader Kimmi N KN Wong Jane D JD

Journal of clinical microbiology 20021101 11

The incidence of serogroup Y meningococcal disease has increased recently in the United States. Here, we describe the development of a 5' exonuclease assay for the detection of serogroup Y Neisseria meningitidis and demonstrate the usefulness of this assay for resolving serogroup identification of strains that are resistant to conventional serogrouping and for the nonculture identification of serogroup Y meningococcal disease. ...[more]

PMID: 12409421

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