Ontology highlight
ABSTRACT:
SUBMITTER: Inoue M
PROVIDER: S-EPMC1400603 | biostudies-literature | 2004 Mar
REPOSITORIES: biostudies-literature
Inoue Masashi M Reed Danielle R DR Li Xia X Tordoff Michael G MG Beauchamp Gary K GK Bachmanov Alexander A AA
The Journal of neuroscience : the official journal of the Society for Neuroscience 20040301 9
Recent studies have shown that the T1R3 receptor protein encoded by the Tas1r3 gene is involved in transduction of sweet taste. To assess ligand specificity of the T1R3 receptor, we analyzed the association of Tas1r3 allelic variants with taste responses in mice. In the F2 hybrids between the C57BL/6ByJ (B6) and 129P3/J (129) inbred mouse strains, we determined genotypes of markers on chromosome 4, where Tas1r3 resides, measured consumption of taste solutions presented in two-bottle preference t ...[more]