Ontology highlight
ABSTRACT:
SUBMITTER: Gunel-Ozcan A
PROVIDER: S-EPMC1402308 | biostudies-literature | 2006 Feb
REPOSITORIES: biostudies-literature
Gunel-Ozcan Aysen A Alyilmaz-Bekmez Sibel S Guler Emine Nilufer EN Guc Dicle D
BMC cancer 20060219
<h4>Background</h4>The hereditary hemochromatosis gene HFE plays a pivotal role in iron homeostasis. The association between cancer and HFE hetero- or homozygosity has previously been shown including hepatocellular and nonhepatocellular malignancies. This study was performed to compare frequencies of HFE C282Y and H63D variants in Turkish women with breast cancer and healthy controls.<h4>Methods</h4>Archived DNA samples of Hacettepe University Oncology Institute were used in this study. The HFE ...[more]