Ontology highlight
ABSTRACT:
SUBMITTER: Pichon JP
PROVIDER: S-EPMC1409818 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Pichon Jean-Philippe JP Bonnaud Bertrand B Cleuziat Philippe P Mallet François F
Nucleic acids research 20060322 6
Human endogenous retroviruses (HERVs) can be divided into distinct families of tens to thousands of paralogous loci. The expression of HERV elements has been detected in all tissues tested to date, particularly germ cells, embryonic tissues and neoplastic tissues. Hence, the study of HERV expression could represent added value in cancer diagnosis. We developed a quantitative assay combining a multiplex degenerate PCR (MD-PCR) amplification, based on the relative conservation of the pol genes, an ...[more]