Ontology highlight
ABSTRACT:
SUBMITTER: Iuchi S
PROVIDER: S-EPMC1413677 | biostudies-literature | 2006 Feb
REPOSITORIES: biostudies-literature
Iuchi Shiro S Dabelsteen Sally S Easley Karen K Rheinwald James G JG Green Howard H
Proceedings of the National Academy of Sciences of the United States of America 20060130 6
Cells of the human embryonic stem (hES) cell line H9, when cultured in the form of embryoid bodies, give rise to cells with markers of the keratinocyte of stratified squamous epithelia. Keratinocytes also form in nodules produced in scid mice by injected H9 cells; the hES-derived keratinocytes could be recovered in culture, where their colonies underwent a peculiar form of fragmentation. Whether formed from embryoid bodies or in nodules, hES-derived keratinocytes differed from postnatal keratino ...[more]