Ontology highlight
ABSTRACT:
SUBMITTER: Noirot-Gros MF
PROVIDER: S-EPMC1413692 | biostudies-literature | 2006 Feb
REPOSITORIES: biostudies-literature
Noirot-Gros Marie-Françoise MF Velten M M Yoshimura M M McGovern S S Morimoto T T Ehrlich S D SD Ogasawara N N Polard P P Noirot Philippe P
Proceedings of the National Academy of Sciences of the United States of America 20060206 7
The regulation of initiation of DNA replication is crucial to ensure that the genome is replicated only once per cell cycle. In the Gram-positive bacterium Bacillus subtilis, the function of the YabA protein in initiation control was assigned based on its interaction with the DnaA initiator and the DnaN sliding clamp in the yeast two-hybrid and on the overinitiation phenotype observed in a yabA null strain. However, YabA is unrelated to known regulators of initiation and interacts with several a ...[more]