The expression profile of microRNAs in mouse embryos.
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ABSTRACT:
SUBMITTER: Mineno J
PROVIDER: S-EPMC1421506 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Publications
The expression profile of microRNAs in mouse embryos.
Mineno Junichi J Okamoto Sachiko S Ando Tatsuya T Sato Masahiro M Chono Hideto H Izu Hiroyuki H Takayama Masanori M Asada Kiyozo K Mirochnitchenko Oleg O Inouye Masayori M Kato Ikunoshin I
Nucleic acids research 20060331 6
MicroRNAs (miRNAs), which are non-coding RNAs 18-25 nt in length, regulate a variety of biological processes, including vertebrate development. To identify new species of miRNA and to simultaneously obtain a comprehensive quantitative profile of small RNA expression in mouse embryos, we used the massively parallel signature sequencing technology that potentially identifies virtually all of the small RNAs in a sample. This approach allowed us to detect a total of 390 miRNAs, including 195 known m ...[more]
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