A single-copy gene encodes Kex1, a serine endoprotease of Pneumocystis jiroveci.
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ABSTRACT:
SUBMITTER: Kutty G
PROVIDER: S-EPMC143410 | biostudies-literature | 2003 Jan
REPOSITORIES: biostudies-literature
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A single-copy gene encodes Kex1, a serine endoprotease of Pneumocystis jiroveci.
Kutty Geetha G Kovacs Joseph A JA
Infection and immunity 20030101 1
We have cloned and characterized the kex1 gene of Pneumocystis jiroveci. Unlike the case for Pneumocystis carinii, in which the homologous PRT-1 genes are multicopy, kex1 is a single-copy gene encoding a protein homologous to fungal serine endoproteases, which localize to the Golgi apparatus. Thus, substantial biological differences can be seen among Pneumocystis species. ...[more]
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