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Amplification of the Gene Ontology annotation of Affymetrix probe sets.


ABSTRACT: BACKGROUND: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete annotations which is not always desirable for microarray experiment evaluation. RESULTS: Here we present a protocol to amplify the set of Gene Ontology annotations associated to Affymetrix DNA microarray probe sets using information from related databases. CONCLUSION: Predicted novel annotations and the evidence producing them can be accessed at Probe2GO: http://www.ogic.ca/p2g. Scripts are available on demand.

SUBMITTER: Muro EM 

PROVIDER: S-EPMC1435773 | biostudies-literature | 2006

REPOSITORIES: biostudies-literature

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Amplification of the Gene Ontology annotation of Affymetrix probe sets.

Muro Enrique M EM   Perez-Iratxeta Carolina C   Andrade-Navarro Miguel A MA  

BMC bioinformatics 20060320


<h4>Background</h4>The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete annotations which is not always desirable for microarray experiment evaluation.<h4>Results</h4>Here we present a protocol to amplify the set of Gene Ontology annotations associated to Affymetrix DNA microarray probe sets using information from related databases.<h4>Conclusion</h4>Predicted novel annotations and th  ...[more]

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