Identification of Nudix hydrolase family members with an antimutator role in Mycobacterium tuberculosis and Mycobacterium smegmatis.
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ABSTRACT:
SUBMITTER: Dos Vultos T
PROVIDER: S-EPMC1446978 | biostudies-literature | 2006 Apr
REPOSITORIES: biostudies-literature
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Identification of Nudix hydrolase family members with an antimutator role in Mycobacterium tuberculosis and Mycobacterium smegmatis.
Dos Vultos T T Blázquez J J Rauzier J J Matic I I Gicquel B B
Journal of bacteriology 20060401 8
Mycobacterium tuberculosis and Mycobacterium smegmatis MutT1, MutT2, MutT3, and Rv3908 (MutT4) enzymes were screened for an antimutator role. Results indicate that both MutT1, in M. tuberculosis and M. smegmatis, and MutT4, in M. smegmatis, have that role. Furthermore, an 8-oxo-guanosine triphosphatase function for MutT1 and MutT2 is suggested. ...[more]
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