Ontology highlight
ABSTRACT:
SUBMITTER: Lemaire M
PROVIDER: S-EPMC1448853 | biostudies-literature | 2004 Oct
REPOSITORIES: biostudies-literature
Genetics 20041001 2
We isolated a mutant, rag17, which is impaired in glucose induction of expression of the major glucose transporter gene RAG1. The RAG17 gene encodes a protein 87% identical to S. cerevisiae enolases (Eno1 and Eno2). The Kleno null mutant showed no detectable enolase enzymatic activity and has severe growth defects on glucose and gluconeogenic carbon sources, indicating that K. lactis has a single enolase gene. In addition to RAG1, the transcription of several glycolytic genes was also strongly r ...[more]