Ontology highlight
ABSTRACT:
SUBMITTER: Bartolome C
PROVIDER: S-EPMC1449532 | biostudies-literature | 2005 Mar
REPOSITORIES: biostudies-literature
Bartolomé Carolina C Maside Xulio X Yi Soojin S Grant Anna L AL Charlesworth Brian B
Genetics 20041115 3
We have investigated patterns of within-species polymorphism and between-species divergence for synonymous and nonsynonymous variants at a set of autosomal and X-linked loci of Drosophila miranda. D. pseudoobscura and D. affinis were used for the between-species comparisons. The results suggest the action of purifying selection on nonsynonymous, polymorphic variants. Among synonymous polymorphisms, there is a significant excess of synonymous mutations from preferred to unpreferred codons and of ...[more]