Ontology highlight
ABSTRACT:
SUBMITTER: Keely SP
PROVIDER: S-EPMC1449779 | biostudies-literature | 2005 Aug
REPOSITORIES: biostudies-literature
Keely Scott P SP Renauld Hubert H Wakefield Ann E AE Cushion Melanie T MT Smulian A George AG Fosker Nigel N Fraser Audrey A Harris David D Murphy Lee L Price Claire C Quail Michael A MA Seeger Kathy K Sharp Sarah S Tindal Carolyn J CJ Warren Tim T Zuiderwijk Eduard E Barrell Barclay G BG Stringer James R JR Hall Neil N
Genetics 20050618 4
In the fungus Pneumocystis carinii, at least three gene families (PRT1, MSR, and MSG) have the potential to generate high-frequency antigenic variation, which is likely to be a strategy by which this parasitic fungus is able to prolong its survival in the rat lung. Members of these gene families are clustered at chromosome termini, a location that fosters recombination, which has been implicated in selective expression of MSG genes. To gain insight into the architecture, evolution, and regulatio ...[more]