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Stress by heat shock induces massive down regulation of genes and allows differential allelic expression of the Gal/GalNAc lectin in Entamoeba histolytica.


ABSTRACT: Gene expression analysis by microarray assay revealed that when exposed to stress, Entamoeba histolytica exhibits a specific heat shock response, together with a dramatic overall reduction in gene transcription as well as differential allelic expression of key genes participating in virulence, such as the galactose/N-acetylgalactosamine (Gal/GalNAc) lectin.

SUBMITTER: Weber C 

PROVIDER: S-EPMC1459685 | biostudies-literature | 2006 May

REPOSITORIES: biostudies-literature

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Stress by heat shock induces massive down regulation of genes and allows differential allelic expression of the Gal/GalNAc lectin in Entamoeba histolytica.

Weber Christian C   Guigon Ghislaine G   Bouchier Christiane C   Frangeul Lionel L   Moreira Sandrine S   Sismeiro Odile O   Gouyette Catherine C   Mirelman David D   Coppee Jean Yves JY   Guillén Nancy N  

Eukaryotic cell 20060501 5


Gene expression analysis by microarray assay revealed that when exposed to stress, Entamoeba histolytica exhibits a specific heat shock response, together with a dramatic overall reduction in gene transcription as well as differential allelic expression of key genes participating in virulence, such as the galactose/N-acetylgalactosamine (Gal/GalNAc) lectin. ...[more]

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