Ontology highlight
ABSTRACT:
SUBMITTER: Riley LW
PROVIDER: S-EPMC1464913 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
The Journal of clinical investigation 20060601 6
Mycolic acids and structures attached to them constitute a major part of the protective envelope of Mycobacterium tuberculosis, and for this reason, their role in tuberculosis pathogenesis has been extensively studied. In this issue of the JCI, Rao et al. examine the effect of trans-cyclopropanation of oxygenated mycolic acids attached to trehalose dimycolate (TDM) on the murine immune response to infection (see the related article beginning on page 1660). Surprisingly, they found that an M. tub ...[more]