Ontology highlight
ABSTRACT:
SUBMITTER: Tobiason DM
PROVIDER: S-EPMC1470461 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Tobiason Deborah M DM Seifert H Steven HS
PLoS biology 20060601 6
We show using several methodologies that the Gram-negative, diplococcal-bacterium Neisseria gonorrhoeae has more than one complete genome copy per cell. Gene dosage measurements demonstrated that only a single replication initiation event per chromosome occurs per round of cell division, and that there is a single origin of replication. The region containing the origin does not encode any genes previously associated with bacterial origins of replication. Quantitative PCR results showed that ther ...[more]