Ontology highlight
ABSTRACT:
SUBMITTER: Yamauchi H
PROVIDER: S-EPMC1479588 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Yamauchi Hajime H Hotta Yuhei Y Konishi Morichika M Miyake Ayumi A Kawahara Atsuo A Itoh Nobuyuki N
EMBO reports 20060413 6
Fibroblast growth factors (Fgfs) function as key secreted signalling molecules in many developmental events. The zebrafish is a powerful model system for the investigation of embryonic vertebrate haematopoiesis. Although the effects of Fgf signalling on haematopoiesis in vitro have been reported, the functions of Fgf signalling in haematopoiesis in vivo remain to be explained. We identified Fgf21 in zebrafish embryos. Fgf21-knockdown zebrafish embryos lacked erythroid and myeloid cells but not b ...[more]