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Total synthesis of (+)-dactylolide.

ABSTRACT: [reaction: see text] The development of an approach leading to the total synthesis of dactylolide is described. The key features of this route include a catalytic asymmetric allylation, a diastereoselective pyran annulation, and a Horner-Wadsworth-Emmons macrocyclization.

SUBMITTER: Sanchez CC

PROVIDER: S-EPMC1480405 | biostudies-literature | 2005 Jul

REPOSITORIES: biostudies-literature

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Total synthesis of (+)-dactylolide.

Sanchez Carina C CC Keck Gary E GE

Organic letters 20050701 14

[reaction: see text] The development of an approach leading to the total synthesis of dactylolide is described. The key features of this route include a catalytic asymmetric allylation, a diastereoselective pyran annulation, and a Horner-Wadsworth-Emmons macrocyclization. ...[more]

PMID: 15987203

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