Ontology highlight
ABSTRACT:
SUBMITTER: Suyama M
PROVIDER: S-EPMC1484586 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Suyama Mikita M Harrington Eoghan E Bork Peer P Torrents David D
PLoS computational biology 20060516 6
The identification and classification of genes and pseudogenes in duplicated regions still constitutes a challenge for standard automated genome annotation procedures. Using an integrated homology and orthology analysis independent of current gene annotation, we have identified 9,484 and 9,017 gene duplicates in human and mouse, respectively. On the basis of the integrity of their coding regions, we have classified them into functional and inactive duplicates, allowing us to define the first con ...[more]