Ontology highlight
ABSTRACT:
SUBMITTER: Trask BC
PROVIDER: S-EPMC14862 | biostudies-literature | 2000 May
REPOSITORIES: biostudies-literature
Trask B C BC Trask T M TM Broekelmann T T Mecham R P RP
Molecular biology of the cell 20000501 5
MAGP-1 and fibrillin-1, two protein components of extracellular microfibrils, were shown by immunoprecipitation studies to interact with the chondroitin sulfate proteoglycan decorin in the medium of cultured fetal bovine chondrocytes. Decorin interacted with each protein individually and with both proteins together to form a ternary complex. Expression of truncated fibrillin-1 proteins in Chinese hamster ovary cells localized proteoglycan binding to an amino-terminal region near the proline-rich ...[more]