Ontology highlight
ABSTRACT:
SUBMITTER: Chen SP
PROVIDER: S-EPMC1488868 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Chen Shee-Ping SP Tsai Shih-Tzu ST Jao Shu-Wen SW Huang Yen-Lun YL Chao Yu-Chen YC Chen Yi-Lin YL Wu Chang-Chieh CC Lin Shinn-Zong SZ Harn Horng-Jyh HJ
BMC cancer 20060329
<h4>Background</h4>Colorectal cancer (CRC), which has become especially prevalent in developed countries, is currently the third highest cause of cancer mortality in Taiwan. Mutation of the adenomatous polyposis coli (APC) gene, a tumour suppressor, is thought to be an early event in colorectal tumourigenesis. To date, however, no large-scale screening for APC gene variants in Chinese subjects has been performed. The present study was undertaken to identify APC gene variants that are significant ...[more]