Evolutionary history of the closely related group 2 coronaviruses: porcine hemagglutinating encephalomyelitis virus, bovine coronavirus, and human coronavirus OC43.
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ABSTRACT:
SUBMITTER: Vijgen L
PROVIDER: S-EPMC1489060 | biostudies-literature | 2006 Jul
REPOSITORIES: biostudies-literature
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Evolutionary history of the closely related group 2 coronaviruses: porcine hemagglutinating encephalomyelitis virus, bovine coronavirus, and human coronavirus OC43.
Vijgen Leen L Keyaerts Els E Lemey Philippe P Maes Piet P Van Reeth Kristien K Nauwynck Hans H Pensaert Maurice M Van Ranst Marc M
Journal of virology 20060701 14
The close genetic and antigenic relatedness among the group 2 coronaviruses human coronavirus OC43 (HCoV-OC43), bovine coronavirus (BCoV), and porcine hemagglutinating encephalomyelitis virus (PHEV) suggests that these three viruses with different host specificities diverged fairly recently. In this study, we determined the complete genomic sequence of PHEV (strain PHEV-VW572), revealing the presence of a truncated group 2-specific ns2 gene in PHEV in comparison to other group 2 coronaviruses. U ...[more]
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