Ontology highlight
ABSTRACT:
SUBMITTER: Cervantes MD
PROVIDER: S-EPMC1489118 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Cervantes Marcella D MD Coyne Robert S RS Xi Xiaohui X Yao Meng-Chao MC
Molecular and cellular biology 20060601 12
The macronucleus of the binucleate ciliate Tetrahymena thermophila contains fragmented and amplified chromosomes that do not have centromeres, eliminating the possibility of mitotic nuclear division. Instead, the macronucleus divides by amitosis with random segregation of these chromosomes without detectable chromatin condensation. This amitotic division provides a special opportunity for studying the roles of mitotic proteins in segregating acentric chromatin. The Smc4 protein is a core compone ...[more]