Identification of a DNA methyltransferase gene carried on a pathogenicity island-like element (VPAI) in Vibrio parahaemolyticus and its prevalence among clinical and environmental isolates.
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ABSTRACT:
SUBMITTER: Wang HZ
PROVIDER: S-EPMC1489626 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
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Identification of a DNA methyltransferase gene carried on a pathogenicity island-like element (VPAI) in Vibrio parahaemolyticus and its prevalence among clinical and environmental isolates.
Wang Hui-zhen HZ Wong Minnie M L MM O'Toole Desmond D Mak Mandy M H MM Wu Rudolf S S RS Kong Richard Y C RY
Applied and environmental microbiology 20060601 6
In this study we identified a putative virulence-associated DNA methyltransferase (MTase) gene carried on a novel 22.79-kb pathogenicity island-like element (VPAI) in V. parahaemolyticus. The V. parahaemolyticus MTase gene was shown by PCR to be prevalent (>98%) in pandemic thermostable direct hemolysin gene-positive isolates, which suggests that VPAI may confer unique virulence traits to pandemic strains of V. parahaemolyticus. ...[more]
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