Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez E
PROVIDER: S-EPMC148971 | biostudies-literature | 2003 Jan
REPOSITORIES: biostudies-literature
Rodríguez Eliana E Laviña Magela M
Antimicrobial agents and chemotherapy 20030101 1
It had been previously determined that the presence of F(o)F(1) ATP synthase was required for microcin H47 antibiotic action. In this work, microcin-resistant atp mutants were genetically analyzed. Their mutations, originated by Tn5 insertion, in all cases were found to affect determinants for the F(o) portion of ATP synthase. To discern if microcin action required the presence of the entire complex or if the F(o) proton channel would suffice, recombinant plasmids carrying different segments of ...[more]