Ontology highlight
ABSTRACT:
SUBMITTER: Puskas LG
PROVIDER: S-EPMC149875 | biostudies-literature | 2003 Feb
REPOSITORIES: biostudies-literature
Puskás László G LG Kitajka Klára K Nyakas Csaba C Barcelo-Coblijn Gwendolyn G Farkas Tibor T
Proceedings of the National Academy of Sciences of the United States of America 20030203 4
Reduced brain levels of long chain polyunsaturated fatty acids [arachidonic acid and docosahexanoic acid (DHA)] are observed in elderly subjects and patients with Alzheimer's disease. To determine the effects of n-3 fatty acids on aged rat brain, 2-year-old rats were fed fish oil (27% DHA content) for 1 month, and gene expression analysis and fatty acid and molecular species composition of the major phospholipid species were assessed. No significant alteration could be observed in the fatty acid ...[more]