Identification and functional characterization of Sphingomonas macrogolitabida strain TFA genes involved in the first two steps of the tetralin catabolic pathway.
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ABSTRACT:
SUBMITTER: Moreno-Ruiz E
PROVIDER: S-EPMC150124 | biostudies-literature | 2003 Mar
REPOSITORIES: biostudies-literature
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Identification and functional characterization of Sphingomonas macrogolitabida strain TFA genes involved in the first two steps of the tetralin catabolic pathway.
Moreno-Ruiz Emilia E Hernáez María José MJ Martínez-Pérez Olga O Santero Eduardo E
Journal of bacteriology 20030301 6
Five genes involved in the two initial steps of the tetralin biodegradation pathway of Sphingomonas macrogolitabida strain TFA have been characterized. ThnA1A2 and ThnA3A4, components of the ring-hydroxylating dioxygenase, were encoded in divergently transcribed operons. ThnA1, ThnA2, and ThnA3 were essential for tetralin ring-hydroxylating dioxygenase activity. ThnB was identified as a dehydrogenase required for tetralin biodegradation. ...[more]
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