Ontology highlight
ABSTRACT:
SUBMITTER: Schmidt NO
PROVIDER: S-EPMC1501284 | biostudies-literature | 2005 Jun
REPOSITORIES: biostudies-literature
Neoplasia (New York, N.Y.) 20050601 6
The transplantation of neural stem cells (NSCs) offers a new potential therapeutic approach as a cell-based delivery system for gene therapy in brain tumors. This is based on the unique capacity of NSCs to migrate throughout the brain and to target invading tumor cells. However, the signals controlling the targeted migration of transplanted NSCs are poorly defined. We analyzed the in vitro and in vivo effects of angiogenic growth factors and protein extracts from surgical specimens of brain tumo ...[more]