The nitrilase superfamily: classification, structure and function.
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ABSTRACT:
SUBMITTER: Pace HC
PROVIDER: S-EPMC150437 | biostudies-literature | 2001
REPOSITORIES: biostudies-literature
Publications
The nitrilase superfamily: classification, structure and function.
Genome biology 20010115 1
The nitrilase superfamily consists of thiol enzymes involved in natural product biosynthesis and post-translational modification in plants, animals, fungi and certain prokaryotes. On the basis of sequence similarity and the presence of additional domains, the superfamily can be classified into 13 branches, nine of which have known or deduced specificity for specific nitrile- or amide-hydrolysis or amide-condensation reactions. Genetic and biochemical analysis of the family members and their asso ...[more]
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