Ontology highlight
ABSTRACT:
SUBMITTER: Orlova EV
PROVIDER: S-EPMC151052 | biostudies-literature | 2003 Mar
REPOSITORIES: biostudies-literature
Orlova Elena V EV Gowen Brent B Dröge Anja A Stiege Asita A Weise Frank F Lurz Rudi R van Heel Marin M Tavares Paulo P
The EMBO journal 20030301 6
In tailed bacteriophages and herpes viruses, the viral DNA is packaged through the portal protein channel. Channel closure is essential to prevent DNA release after packaging. Here we present the connector structure from bacteriophage SPP1 using cryo-electron microscopy and single particle analysis. The multiprotein complex comprises the portal protein gp6 and the head completion proteins gp15 and gp16. Although we show that gp6 in the connector has a fold similar to that of the isolated portal ...[more]