Ontology highlight
ABSTRACT:
SUBMITTER: Gilland E
PROVIDER: S-EPMC15109 | biostudies-literature | 1999 Jan
REPOSITORIES: biostudies-literature
Gilland E E Miller A L AL Karplus E E Baker R R Webb S E SE
Proceedings of the National Academy of Sciences of the United States of America 19990101 1
Oscillations of cytosolic free calcium levels have been shown to influence gene regulation and cell differentiation in a variety of model systems. Intercellular calcium waves thus present a plausible mechanism for coordinating cellular processes during embryogenesis. Herein we report use of aequorin and a photon imaging microscope to directly observe a rhythmic series of intercellular calcium waves that circumnavigate zebrafish embryos over a 10-h period during gastrulation and axial segmentatio ...[more]