Ontology highlight
ABSTRACT:
SUBMITTER: Hauck B
PROVIDER: S-EPMC15176 | biostudies-literature | 1999 Jan
REPOSITORIES: biostudies-literature
Hauck B B Gehring W J WJ Walldorf U U
Proceedings of the National Academy of Sciences of the United States of America 19990101 2
The development of the Drosophila compound eye requires the function of a set of evolutionarily conserved genes. Among these, the Drosophila Pax-6 gene eyeless (ey) plays a major role. ey has been considered a master control gene of eye development in the animal kingdom because targeted expression of ey and vertebrate as well as invertebrate homologs lead to the formation of ectopic eyes in Drosophila. We demonstrate that an intron of the ey gene contains an enhancer that regulates the eye speci ...[more]