Regulation of ovulation rate in mammals: contribution of sheep genetic models.
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SUBMITTER: Fabre S
PROVIDER: S-EPMC1524776 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
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Regulation of ovulation rate in mammals: contribution of sheep genetic models.
Fabre Stéphane S Pierre Alice A Mulsant Philippe P Bodin Loys L Di Pasquale Elisa E Persani Luca L Monget Philippe P Monniaux Danielle D
Reproductive biology and endocrinology : RB&E 20060412
Ovarian folliculogenesis in mammals from the constitution of primordial follicles up to ovulation is a reasonably well understood mechanism. Nevertheless, underlying mechanisms that determine the number of ovulating follicles were enigmatic until the identification of the fecundity genes affecting ovulation rate in sheep, bone morphogenetic protein-15 (BMP-15), growth and differentiation factor-9 (GDF-9) and BMP receptor-1B (BMPR-1B). In this review, we focus on the use of these sheep genetic mo ...[more]
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