Ontology highlight
ABSTRACT:
SUBMITTER: Hein JE
PROVIDER: S-EPMC1524859 | biostudies-literature | 2005 Jun
REPOSITORIES: biostudies-literature
Organic letters 20050601 13
[reaction: see text] A series of asymmetric free-radical-mediated intermolecular conjugate additions using a fluorous oxazolidinone chiral auxiliary has been completed. The fluorous auxiliary facilitated product isolation using fluorous solid phase extractions (FSPE), effectively removing excess organic and organometallic reagents. Parallel reactions carried out with a similar but nonfluorous norephedrine-derived oxazolidinone demonstrated the superior stereoselectivity and purification obtainab ...[more]