Ontology highlight
ABSTRACT:
SUBMITTER: Humphries KH
PROVIDER: S-EPMC152685 | biostudies-literature | 2003 Apr
REPOSITORIES: biostudies-literature
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030401 8
Until recently, observational studies suggested a decreased risk of cardiovascular disease, osteoporotic fractures, cognitive decline and colon cancer with the use of hormone replacement therapy (HRT). Recent randomized controlled trials have failed to show a protective effect of HRT in reducing the risk of coronary artery disease and instead have revealed an increased risk of heart disease, stroke, invasive breast cancer and venous thromboembolism, but a decreased risk of colorectal cancer and ...[more]