Production of resveratrol in recombinant microorganisms.
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ABSTRACT:
SUBMITTER: Beekwilder J
PROVIDER: S-EPMC1538726 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
Publications
Production of resveratrol in recombinant microorganisms.
Beekwilder Jules J Wolswinkel Rianne R Jonker Harry H Hall Robert R de Vos C H Ric CH Bovy Arnaud A
Applied and environmental microbiology 20060801 8
Resveratrol production in Saccharomyces cerevisiae was compared to that in Escherichia coli. In both systems, 4-coumarate:coenzyme A ligase from tobacco and stilbene synthase from grapes were expressed. When p-coumaric acid was used as the precursor, resveratrol accumulations in the culture medium were observed to be comparable in E. coli (16 mg/liter) and yeast (6 mg/liter). ...[more]
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