A Mutation in the luxS gene influences Listeria monocytogenes biofilm formation.
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ABSTRACT:
SUBMITTER: Sela S
PROVIDER: S-EPMC1538747 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
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A Mutation in the luxS gene influences Listeria monocytogenes biofilm formation.
Sela Shlomo S Frank Shmulik S Belausov Eddy E Pinto Riky R
Applied and environmental microbiology 20060801 8
Using a Vibrio harveyi reporter strain, we demonstrated that Listeria monocytogenes secretes a functional autoinducer 2 (AI-2)-like signal. A luxS-deficient mutant produced a denser biofilm and attached to a glass surface 19-fold better than the parent strain. Exogenous AI-2 failed to restore the wild-type phenotype to the mutant. It seems that an intact luxS gene is associated with repression of components required for attachment and biofilm formation. ...[more]
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