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A nutrient uptake role for bacterial cell envelope extensions.

ABSTRACT: Bacteria exist in a variety of morphologies, but the relationship between cellular forms and biological functions remains poorly understood. We show that stalks (prosthecae), cylindrical extensions of the Caulobacter crescentus cell envelope, can take up and hydrolyze organic phosphate molecules and contain the high-affinity phosphate-binding protein PstS, but not PstA, a protein that is required for transport of phosphate into the cytoplasm. Therefore, uptake, hydrolysis, and periplasmic binding of a phosphate source can take place in the stalk, but high-affinity import must take place in the cell body. Furthermore, by using analytical modeling, we illustrate the biophysical advantage of the stalk as a morphological adaptation to the diffusion-limited, oligotrophic environments where C. crescentus thrives. This advantage is due to the fact that a stalk is long and thin, a favorable shape for maximizing contact with diffusing nutrients while minimizing increases in both surface area and cell volume.

SUBMITTER: Wagner JK

PROVIDER: S-EPMC1544245 | biostudies-literature | 2006 Aug

REPOSITORIES: biostudies-literature

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A nutrient uptake role for bacterial cell envelope extensions.

Wagner Jennifer K JK Setayeshgar Sima S Sharon Laura A LA Reilly James P JP Brun Yves V YV

Proceedings of the National Academy of Sciences of the United States of America 20060721 31

Bacteria exist in a variety of morphologies, but the relationship between cellular forms and biological functions remains poorly understood. We show that stalks (prosthecae), cylindrical extensions of the Caulobacter crescentus cell envelope, can take up and hydrolyze organic phosphate molecules and contain the high-affinity phosphate-binding protein PstS, but not PstA, a protein that is required for transport of phosphate into the cytoplasm. Therefore, uptake, hydrolysis, and periplasmic bindin ...[more]

PMID: 16861302

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Dataset Information

A nutrient uptake role for bacterial cell envelope extensions.

Publications

A nutrient uptake role for bacterial cell envelope extensions.

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