Ontology highlight
ABSTRACT:
SUBMITTER: Luttgen H
PROVIDER: S-EPMC15522 | biostudies-literature | 2000 Feb
REPOSITORIES: biostudies-literature
Lüttgen H H Rohdich F F Herz S S Wungsintaweekul J J Hecht S S Schuhr C A CA Fellermeier M M Sagner S S Zenk M H MH Bacher A A Eisenreich W W
Proceedings of the National Academy of Sciences of the United States of America 20000201 3
A comparative analysis of all published complete genomes indicated that the putative orthologs of the unannotated ychB gene of Escherichia coli follow the distribution of the dxs, dxr, and ygbP genes, which have been shown to specify enzymes of the deoxyxylulose phosphate pathway of terpenoid biosynthesis, thus suggesting that the hypothetical YchB protein also is involved in that pathway. To test this hypothesis, the E. coli ychB gene was expressed in a homologous host. The recombinant protein ...[more]