Ontology highlight
ABSTRACT:
SUBMITTER: Jin P
PROVIDER: S-EPMC1557669 | biostudies-literature | 2006 Jun
REPOSITORIES: biostudies-literature
Journal of translational medicine 20060628
Experimentally, interleukin-2 (IL-2) exerts complex immunological functions promoting the proliferation, survival and activation of T cells on one hand and inducing immune regulatory mechanisms on the other. This complexity results from a cross talk among immune cells which sways the effects of IL-2 according to the experimental or clinical condition tested. Recombinant IL-2 (rIL-2) stimulation of peripheral blood mononuclear cells (PBMC) from 47 donors of different genetic background induced ge ...[more]