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Salmonella enterica serovar typhi strains isolated in Korea containing a multidrug resistance class 1 integron.

ABSTRACT: Six strains of Salmonella enterica serovar Typhi which were resistant to ampicillin, chloramphenicol, trimethoprim-sulfamethoxazole, streptomycin, tetracycline, and gentamicin were isolated in Korea. This multidrug resistance was transferred by a conjugative plasmid of about 50 kb. The plasmid harbored a class 1 integron, which included six resistance genes, aacA4b, catB8, aadA1, dfrA1, aac(6')-IIa, and the novel blaP2, in that order. All of the isolates showed the same-size plasmids and the same ribotyping patterns, which suggests a clonal spread of these multidrug-resistant isolates.

SUBMITTER: Pai H

PROVIDER: S-EPMC155850 | biostudies-literature | 2003 Jun

REPOSITORIES: biostudies-literature

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Salmonella enterica serovar typhi strains isolated in Korea containing a multidrug resistance class 1 integron.

Pai Hyunjoo H Byeon Jeong-hum JH Yu Sunmi S Lee Bok Kwon BK Kim Shukho S

Antimicrobial agents and chemotherapy 20030601 6

Six strains of Salmonella enterica serovar Typhi which were resistant to ampicillin, chloramphenicol, trimethoprim-sulfamethoxazole, streptomycin, tetracycline, and gentamicin were isolated in Korea. This multidrug resistance was transferred by a conjugative plasmid of about 50 kb. The plasmid harbored a class 1 integron, which included six resistance genes, aacA4b, catB8, aadA1, dfrA1, aac(6')-IIa, and the novel blaP2, in that order. All of the isolates showed the same-size plasmids and the sam ...[more]

PMID: 12760886

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