Genome size and metabolic intensity in tetrapods: a tale of two lines.

ABSTRACT: We show the negative link between genome size and metabolic intensity in tetrapods, using the heart index (relative heart mass) as a unified indicator of metabolic intensity in poikilothermal and homeothermal animals. We found two separate regression lines of heart index on genome size for reptiles-birds and amphibians-mammals (the slope of regression is steeper in reptiles-birds). We also show a negative correlation between GC content and nucleosome formation potential in vertebrate DNA, and, consistent with this relationship, a positive correlation between genome GC content and nuclear size (independent of genome size). It is known that there are two separate regression lines of genome GC content on genome size for reptiles-birds and amphibians-mammals: reptiles-birds have the relatively

SUBMITTER: Vinogradov AE 

PROVIDER: S-EPMC1560010 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature