Ontology highlight
ABSTRACT:
SUBMITTER: Wootton SK
PROVIDER: S-EPMC1563922 | biostudies-literature | 2006 Sep
REPOSITORIES: biostudies-literature
Wootton Sarah K SK Halbert Christine L CL Miller A Dusty AD
Journal of virology 20060901 18
Jaagsiekte sheep retrovirus (JSRV) induces bronchioalveolar tumors in sheep and goats. Expression of the JSRV envelope (Env) protein in mouse airway epithelial cells induces similar tumors, indicating that Env expression is sufficient for tissue-specific tumor formation. Enzootic nasal tumor virus (ENTV) is related to JSRV but induces tumors in the nasal epithelium of sheep and goats. Here we found that ENTV Env can also induce tumors in mice but, unexpectedly, with a phenotype identical to that ...[more]