Ontology highlight
ABSTRACT:
SUBMITTER: Ahn HJ
PROVIDER: S-EPMC156765 | biostudies-literature | 2003 Jun
REPOSITORIES: biostudies-literature
Ahn Hyung Jun HJ Kim Hyeon-Woo HW Yoon Hye-Jin HJ Lee Byung Il BI Suh Se Won SW Yang Jin Kuk JK
The EMBO journal 20030601 11
tRNA(m(1)G37)methyltransferase (TrmD) catalyzes the transfer of a methyl group from S-adenosyl-L- methionine (AdoMet) to G(37) within a subset of bacterial tRNA species, which have a G residue at the 36th position. The modified guanosine is adjacent to and 3' of the anticodon and is essential for the maintenance of the correct reading frame during translation. Here we report four crystal structures of TrmD from Haemophilus influenzae, as binary complexes with either AdoMet or S-adenosyl-L-homocy ...[more]