Ontology highlight
ABSTRACT:
SUBMITTER: Guelman S
PROVIDER: S-EPMC1592886 | biostudies-literature | 2006 Oct
REPOSITORIES: biostudies-literature
Guelman Sebastián S Suganuma Tamaki T Florens Laurence L Weake Vikki V Swanson Selene K SK Washburn Michael P MP Abmayr Susan M SM Workman Jerry L JL
Molecular and cellular biology 20061001 19
Histone acetylation provides a switch between transcriptionally repressive and permissive chromatin. By regulating the chromatin structure at specific promoters, histone acetyltransferases (HATs) carry out important functions during differentiation and development of higher eukaryotes. HAT complexes are present in organisms as diverse as Saccharomyces cerevisiae, humans, and flies. For example, the well-studied yeast SAGA is related to three mammalian complexes. We previously identified Drosophi ...[more]