Ontology highlight
ABSTRACT:
SUBMITTER: Wagner B
PROVIDER: S-EPMC1599898 | biostudies-literature | 2006 Sep
REPOSITORIES: biostudies-literature
Wagner B B Tharmann R R Haase I I Fischer M M Bausch A R AR
Proceedings of the National Academy of Sciences of the United States of America 20060908 38
In living cells the mechanical properties of the actin cytoskeleton are defined by the local activation of different actin cross-linking proteins. These proteins consist of actin-binding domains that are separated and geometrically organized by different numbers of rod domains. The detailed molecular structure of the cross-linking molecules determines the structural and mechanical properties of actin networks in vivo. In this study, we systematically investigate the impact of the length of the s ...[more]