Ontology highlight
ABSTRACT:
SUBMITTER: Huang B
PROVIDER: S-EPMC1601958 | biostudies-literature | 2006
REPOSITORIES: biostudies-literature
Huang Bingding B Schroeder Michael M
BMC structural biology 20060924
<h4>Background</h4>Identifying pockets on protein surfaces is of great importance for many structure-based drug design applications and protein-ligand docking algorithms. Over the last ten years, many geometric methods for the prediction of ligand-binding sites have been developed.<h4>Results</h4>We present LIGSITEcsc, an extension and implementation of the LIGSITE algorithm. LIGSITEcsc is based on the notion of surface-solvent-surface events and the degree of conservation of the involved surfac ...[more]