Ontology highlight
ABSTRACT:
SUBMITTER: Krin E
PROVIDER: S-EPMC1610301 | biostudies-literature | 2006 Oct
REPOSITORIES: biostudies-literature
Krin Evelyne E Chakroun Nesrine N Turlin Evelyne E Givaudan Alain A Gaboriau François F Bonne Isabelle I Rousselle Jean-Claude JC Frangeul Lionel L Lacroix Céline C Hullo Marie-Françoise MF Marisa Laetitia L Danchin Antoine A Derzelle Sylviane S
Applied and environmental microbiology 20061001 10
Bacterial virulence is an integrative process that may involve quorum sensing. In this work, we compared by global expression profiling the wild-type entomopathogenic Photorhabdus luminescens subsp. laumondii TT01 to a luxS-deficient mutant unable to synthesize the type 2 quorum-sensing inducer AI-2. AI-2 was shown to regulate more than 300 targets involved in most compartments and metabolic pathways of the cell. AI-2 is located high in the hierarchy, as it controls the expression of several tra ...[more]