Ontology highlight
ABSTRACT:
SUBMITTER: Nakamura M
PROVIDER: S-EPMC1615786 | biostudies-literature | 2004 Jun
REPOSITORIES: biostudies-literature
Nakamura Morio M Matute-Bello Gustavo G Liles W Conrad WC Hayashi Shinichi S Kajikawa Osamu O Lin Shu-Min SM Frevert Charles W CW Martin Thomas R TR
The American journal of pathology 20040601 6
The Fas (CD95)/Fas ligand (CD178) system plays an important role in epithelial damage during the acute respiratory distress syndrome. The goal of this study was to determine whether proximal and distal human lung epithelial cells differ in their sensitivity to Fas ligand (rh-sFasL), and whether the response of lung epithelium to Fas ligation is modulated by proinflammatory cytokines. Although the expression of both Fas message and protein was similar in proximal and distal lung epithelial cells, ...[more]