Ontology highlight
ABSTRACT:
SUBMITTER: Liu Y
PROVIDER: S-EPMC1617227 | biostudies-literature | 2006 Oct
REPOSITORIES: biostudies-literature
Liu Yi Y McNevin John J Cao Jianhong J Zhao Hong H Genowati Indira I Wong Kim K McLaughlin Sherry S McSweyn Matthew D MD Diem Kurt K Stevens Claire E CE Maenza Janine J He Hongxia H Nickle David C DC Shriner Daniel D Holte Sarah E SE Collier Ann C AC Corey Lawrence L McElrath M Juliana MJ Mullins James I JI
Journal of virology 20061001 19
Typically during human immunodeficiency virus type 1 (HIV-1) infection, a nearly homogeneous viral population first emerges and then diversifies over time due to selective forces that are poorly understood. To identify these forces, we conducted an intensive longitudinal study of viral genetic changes and T-cell immunity in one subject at < or =17 time points during his first 3 years of infection, and in his infecting partner near the time of transmission. Autologous peptides covering amino acid ...[more]